EDAP Partners with Diagnostic Center for Disease to Offer Minimally Invasive Ablatherm®-HIFU Treatment to Prostate Cancer Patients in Cancun

Sarasota, Florida – March 30, 2012 – EDAP TMS SA (NASDAQ: EDAP), a global leader in therapeutic ultrasound, announced today that it will partner with Diagnostic Center for Disease, a division of PanAm HIFU, to offer minimally invasive High-Intensity Focused Ultrasound (HIFU) treatment to North American prostate cancer patients, with the installation of an Ablatherm device in Cancun, Mexico. Diagnostic Center for Disease is a urology practice under the medical direction of Dr. Ronald Wheeler in Sarasota, Florida, that provides prostate cancer patients access to Ablatherm-HIFU treatment in London and Cancun.

Ablatherm-HIFU is a procedure where the temperature inside the prostate is raised to 85 degrees Celsius using a focused ultrasound beam to destroy targeted cells. Ablatherm-HIFU technology was approved for treatment in Europe in 1999, and has been shown to have a similar success rate to radical prostatectomy but with the major advantage of using minimally invasive technology with fewer side effects.

Marc Oczachowski, Chief Executive Officer of EDAP TMS, said, “We have received many requests from urologists in the United States to be trained on and have access to Ablatherm-HIFU at offshore locations. We are pleased to announce this partnership agreement with PanAm HIFU and look forward to working with Dr. Wheeler’s medical team, which has experience in treating prostate cancer with Ablatherm-HIFU technology in the United Kingdom. Our new partnership will give PanAm HIFU access to our Ablatherm-HIFU technology in Cancun, Mexico, to treat their prostate cancer patients starting in April 2012.”

Dr. Ronald Wheeler, M.D., Urologist and Medical Director of Diagnostic Center for Disease and PanAm HIFU, said, “We are delighted to offer this beautiful venue to our patients and to the patients of other U.S. physicians who may want to be trained on this exciting robotic Ablatherm technology. Several of our patients have reported positive outcomes after receiving focal prostate cancer treatment with EDAP’s Ablatherm-HIFU device. Cancun offers spectacular ‘medical tourism’ as well as five-star hospital facilities.”

About Diagnostic Center for Disease
Dr. Ronald E. Wheeler is Medical Director of Diagnostic Center for Disease, a division of PanAm HIFU. He diagnoses and treats only prostate disease in a full-time clinical practice in Sarasota, Florida. As an expert in High-Intensity Focused Ultrasound (HIFU), Dr. Wheeler is an acclaimed Urologist who has diagnosed and treated more prostate cancer patients from more countries than any other treating doctor in the world. Please visit www.panamhifu.com for more information.

EDAP TMS SA develops and markets Ablatherm®, the most advanced and clinically proven choice for High-Intensity Focused Ultrasound (HIFU) treatment of localized prostate cancer. HIFU treatment is shown to be a minimally invasive and effective treatment option with a low occurrence of side effects. Ablatherm-HIFU is generally recommended for patients with localized prostate cancer (stages T1-T2) who are not candidates for surgery or who prefer an alternative option, or for patients who failed radiotherapy treatment. Approved in Europe as a treatment for prostate cancer, Ablatherm-HIFU is currently undergoing evaluation in a multi-center U.S. Phase II/III clinical trial under an Investigational Device Exemption (IDE) granted by the FDA, the ENLIGHT U.S. clinical study. The company also is developing this technology for the potential treatment of certain other types of tumors. EDAP TMS SA also produces and commercializes medical equipment (the Sonolith® range) for treatment of urinary tract stones using extra-corporeal shockwave lithotripsy (ESWL). For more information, please visit www.edap-tms.com and www.hifu-planet.com.

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